• 学术活动
  • 学术活动
    2013年生物科学论坛-第二十二期
    发布时间: 2013-11-07
    浏览量:

    报告题目:Insights from the microRNA behaviors in plants

    报 告 人:武 亮  副研究员(中国农业科学院)

    报告时间:11月11日(星期一) 下午15:00

    报告地点:生物楼201室

    摘要:
    As the most important class of small silencing RNAs (sRNAs), microRNAs (miRNAs) are canonically considered to be 20-22 nucleotides (nt) in length and guide targets regulation via mRNA degradation or translation inhibition. A class of 24-nt long miRNAs has been characterized as modulators through DNA methylation for gene expression in rice, implying a more complicated miRNA population in plants. Our recent study found  a Pooideae-specific miRNA that targets florigen genes and regulates flowering time in Brachypodium under different daylength, suggesting that both conserved and non-conserved miRNAs play critical roles in plant growth and adaptation to the environments.

    研究领域:植物小分子RNA作用机制和功能研究
    教育背景:
    1999.9-2003.7    山西农业大学 本科
    2003.9-2006.7    南京农业大学  硕士
    2007.9-2010.6    北京生命科学研究所 北京师范大学 博士
    工作经历:
    2006.7-2007.8           北京生命科学研究所 研究助理
    2010.7- 2010.10   北京生命科学研究所 博士后
    2010.11- 2011.8   德国马普发育生物学研究所 博士后
    2011.9-至今   中国农业科学院作物科学研究所 副研究员
    部分代表文章:
    1)       Wu. L*., Liu. D., Wu. J., Qin.Z., Zhang.R., Li, A., Zhai. W., and Mao. L* (2013) Regulation of FLOWERING LOCUS T by a microRNA inBrachypodium distachyon. The Plant Cell. In press
    2)       Wu. L * (2013) DICER-LIKE1 processed trans-acting siRNAs mediate DNA methylation: Case study of complex small RNA biogenesis and action pathways in plants. Plant Signaling and Behavior, volume 8, issue 1
    3)       Wu. L*., Mao L., and Qi Y. (2012) Roles of DICER-LIKE and ARGONAUTE Proteins in TAS-Derived Small Interfering RNA-Triggered DNA Methylation. Plant Physiology, 160: 990-999
    4)       Wu. L., Zhou, H., Zhang, Q., Zhang, J., Ni, F., Liu, C., and Qi, Y. (2010) DNA methylation mediated by a microRNA pathway. Molecular cell, 38, 465-475 (Cover story) this work was featured in Cell, 141: 556, 2010.
    5)       Wu. L., Zhang Q., Zhou H., Ni F., Wu X., Qi Y. (2009) Rice microRNA effector complexes and targets. The Plant Cell, 21:3421-3435
     

    欢迎各位老师,同学参加!
    生物科学与技术学院
    2013年11月7日