蒋玉祥|教授
研究方向
1. 有花植物雌雄生殖器官协同发育调控。现阶段重点研究花粉管和雌蕊内部结构的协同适应性进化发育机制。
2. O-糖基化修饰调控植物生理活动的机制。结合生物化学、蛋白修饰组学和发育生物学等手段探究两种O-糖基化修饰（O-GlcNAc和O-fucose）在植物器官发育和环境响应中的新功能。
3. 重要针叶树的遗传育种技术创新。结合生物信息学、细胞生物学和分子生物学等手段，解析重要针叶树的生殖发育基因网络，推动遗传转化和育种技术创新。
学习和工作经历
2024-至今， 教授，北京林业大学
2023-2024，“玛丽·居里学者” 博士后研究员, 莱顿大学, 荷兰
2019-2023，博士后研究员, John Innes Centre, 英国
2017-2019，博士后, 清华大学生命科学学院, 北京
2011-2017，硕博连读，中国科学院植物研究所, 北京，专业：发育生物学
2006 -2010，本科, 中国海洋大学，青岛，专业：生物化学与分子生物学
承担项目
国家级高层次青年人才项目。2024-2027，在研，主持
北林科研创新项目个人项目。2025-2027，在研，主持
科研创新项目青年人才项目。2024-2026，在研，主持
北林新进教师科研启动项目。2025-2027，在研，主持
欧盟欧洲地平线-玛丽·居里行动计划（MSCA）项目(Individual Fellowship)，Decoding calcium pathway activated by plant intracellular immune receptors。 2023-2024，结题。主持
英国皇家学会大学研究员项目，Conserved mechanisms regulate symmetry establishment in plant organs，2019-2023，结题。主要参与
国自然基金面上项目，villin调控植物生长发育的机理研究，2020-2023，结题。参与
国自然基金面上项目，拟南芥生殖型ADF功能及活性调控，2017-2020，结题。主要参与
清华-北大生命科学联合中心博士后基金，拟南芥生殖型ADF功能分化和调控的研究。2018-2019，结题。主持
中国博士后科学基金，PLIM蛋白调控拟南芥花粉管极性生长的机制研究。2017-2019，结题。主持
国自然基金青年基金项目，水稻腺苷酸环化酶结合蛋白调控微丝动态的分子机制研究，2015-2017，结题。参与
讲授课程
《生物大数据》本科课程，主讲。
研究成果
- 第一作者（含共同第一作者）和通讯作者的文章：
1. Y. Jiang, S. Curran-French, S. W. H. Koh, I. Jamil, B. Gu, L. Argirò, S. G. Lopez, C. Martins, G. Saalbach & L. Moubayidin. O-glycosylation of the transcription factor SPATULA promotes style development in Arabidopsis. Nature Plants, 2024. 10(2): 283-299. https://doi.org/10.1038/s41477-023-01617-4.
2. J. Wang*, J. Shen*, Y. Xu*, Y. Jiang*, X. Qu, W. Zhao, Y. Wang, S. Huang, Differential sensitivity of ADF isovariants to a pH gradient promotes pollen tube growth. Journal of Cell Biology. 2023. 222(11), e202206074. (*共同第一作者) DOI:10.1083/jcb.202206074.
3. Y. Jiang #, P. Ding #. Calcium Signalling in Plant Immunity: A Spatiotemporally Controlled Symphony. Trends Plant Sci. (2022). 28(1): 74-89. (invited review article. #共同通讯作者. 封面文章) https://doi.org/10.1016/j.tplants.2022.11.001.
4. Y. Jiang, L. Moubayidin. Floral symmetry: The geometry of plant reproduction. Emerging Topics in Life Sciences. (2022). 6(3):259-269 (Invited review article. 封面文章) https://doi.org/10.1042/ETLS20210270.
5. Y. Jiang, Q. Lu, S. Huang, Functional non-equivalence of pollen ADF isovariants in Arabidopsis., Plant J. (2022). 110(4): 1068-1081 https://doi.org/10.1111/tpj.15723.
6. Y. Jiang*, M. Chang*, Y. Lan*, S. Huang, Mechanism of CAP1-mediated apical actin polymerization in pollen tubes., Proc Natl Acad Sci USA. (2019). 116: 12084–12093. (*共同第一作者) https://doi.org/10.1073/pnas.1821639116.
7. Y. Jiang, M. Zhang, S. Huang, Analysis of Actin-Based Intracellular Trafficking in Pollen Tubes., Methods Mol. Biol. (2017). 1662：125–136. Book chapter. https://doi.org/10.1007/978-1-4939-7262-3_11.
8. Y. Jiang*, J. Wang*, Y. Xie, N. Chen, S. Huang, ADF10 shapes the overall organization of apical actin filaments by promoting their turnover and ordering in pollen tubes., J. Cell Sci. (2017). 130: 3988–4001. (*共同第一作者). https://doi.org/10.1242/jcs.207738.
9. Y. Jiang, S. Huang, Direct Visualization and Quantification of the Actin Nucleation and Elongation Events in vitro by TIRF Microscopy, Bio Protoc. (2017). 7(5): e2146 https://doi.org/10.21769/BioProtoc.2146.
10. Y. Zheng*, Y. Xie*, Y. Jiang*, X. Qu, S. Huang, Arabidopsis actin-depolymerizing factor7 severs actin filaments and regulates actin cable turnover to promote normal pollen tube growth., Plant Cell. (2013). 25: 3405–3423. (*共同第一作者) https://doi.org/10.1105/tpc.113.117820.
共同作者的文章：
1. W. Tasker-Brown, S. W. H. Koh, N. Trozzi, K. Maio, I. Jamil, Y. Jiang, M. Majda, R. Smith, L. Moubayidin, An incoherent feed‐forward loop involving bHLH transcription factors, Auxin and CYCLIN‐Ds regulates style radial symmetry establishment in Arabidopsis. Plant Journal. 2024. 119(6), 2885-2903. DOI: 10.1111/tpj.16959.
2. Q. Wang, Y. Xu, S. Zhao, Y. Jiang, R. Yi, Y. Guo, S. Huang, Activation of actin-depolymerizing factor by CDPK16-mediated phosphorylation promotes actin turnover in Arabidopsis pollen tubes. PLoS Biology. 2023. 21(4), e3002073. DOI: 10.1371/journal.pbio.3002073.
3. Y. Chai, D. Tian, Z. Zhu, Y. Jiang, S. Huang, D. Wu, G. Ou, W. Li, Wnt signaling polarizes cortical actin polymerization to increase daughter cell asymmetry., Cell Discov. (2022). 8, 22. https://doi.org/10.1038/s41421-022-00376-4.
4. C. Xie, Y. Jiang, Z. Zhu, S. Huang, W. Li, G. Ou, Actin filament debranching regulates cell polarity during cell migration and asymmetric cell division., Proc Natl Acad Sci USA. (2021). 118(37):e2100805118 https://doi.org/10.1073/pnas.2100805118.
5. W. Zheng, Y. Jiang, X. Wang, S. Huang, M. Yuan, Y. Guo, AP3M harbors actin filament binding activity that is crucial for vacuole morphology and stomatal closure in Arabidopsis., Proc Natl Acad Sci USA. (2019). 116: 18132–18141. https://doi.org/10.1073/pnas.1901431116.
6. R. Zhang*, X. Qu*, M. Zhang*, Y. Jiang, A. Dai, W. Zhao, D. Cao, Y. Lan, R. Yu, H. Wang, S. Huang, The Balance between Actin-Bundling Factors Controls Actin Architecture in Pollen Tubes., iScience. (2019) 16: 162–176. https://doi.org/10.1016/j.isci.2019.05.026.
7. Y. Yang*, Y. Zhang*, W.-J. Li, Y. Jiang, Z. Zhu, H. Hu, W. Li, J.-W. Wu, Z.-X. Wang, M.-Q. Dong, S. Huang, G. Ou, Spectraplakin Induces Positive Feedback between Fusogens and the Actin Cytoskeleton to Promote Cell-Cell Fusion., Dev. Cell. (2017) 41:107-120.e4. https://doi.org/10.1016/j.devcel.2017.03.006.
8. Z. Zhu, Y. Chai, Y. Jiang, W. Li, H. Hu, W. Li, J.-W. Wu, Z.-X. Wang, S. Huang, G. Ou, Functional coordination of WAVE and WASP in c. elegans neuroblast migration., Dev. Cell. (2016). 39: 224–238. https://doi.org/10.1016/j.devcel.2016.09.029.
9. S. Zhao, Y. Jiang, Y. Zhao, S. Huang, M. Yuan, Y. Zhao, Y. Guo, CASEIN KINASE1-LIKE PROTEIN2 Regulates Actin Filament Stability and Stomatal Closure via Phosphorylation of Actin Depolymerizing Factor., Plant Cell. (2016) 28: 1422–1439. https://doi.org/10.1105/tpc.16.00078.
10. T. Cao, L. Sun, Y. Jiang, S. Huang, J. Wang, Z. Chen, Crystal structure of a nuclear actin ternary complex., Proc Natl Acad Sci USA. (2016) 113: 8985–8990. https://doi.org/10.1073/pnas.1602818113.
11. D. Tian, M. Diao, Y. Jiang, L. Sun, Y. Zhang, Z. Chen, S. Huang, G. Ou, Anillin regulates neuronal migration and neurite growth by linking rhog to the actin cytoskeleton., Curr. Biol. (2015) 25: 1135–1145. https://doi.org/10.1016/j.cub.2015.02.072.
12. X. Liu, X. Qu, Y. Jiang, M. Chang, R. Zhang, Y. Wu, Y. Fu, S. Huang, Profilin regulates apical actin polymerization to control polarized pollen tube growth., Mol. Plant. (2015) 8: 1694–1709. https://doi.org/10.1016/j.molp.2015.09.013.
13. X. Qu, Y. Jiang, M. Chang, X. Liu, R. Zhang, S. Huang, Organization and regulation of the actin cytoskeleton in the pollen tube., Front. Plant Sci. (2014). 5:786. https://doi.org/10.3389/fpls.2014.00786.